A molecular-imprint nanosensor for ultrasensitive detection of proteins

A molecular-imprint nanosensor for ultrasensitive detection of proteins.

Molecular imprinting is a technique for preparing polymer scaffolds that function as synthetic receptors. Imprinted polymers that can selectively bind organic compounds have proven useful in sensor development. Although creating synthetic molecular-imprinting polymers that recognize proteins remains challenging, nanodevices and nanomaterials show promise in this area. Here, we show that arrays ...

Ultrasensitive detection of cancer biomarkers in serum by hybrid mechanical and optoplasmonic nanosensor

The blood contains a treasure trove of protein biomarkers, most of them still to discover, which will be crucial for early detection of disease and for personalized medicine 1-4. A key point in this goal will be nanosensors capable of detecting with very high reproducibility biomarkers at concentrations of at least one million times lower than the rest of blood proteins 5-7. In this letter, we ...

Nanosensor Device for Breath Acetone Detection

Nanosensor Device for Breath Acetone Detection L. Wang1, K. Kalyanasundaram2, M. Stanacevic3, and P. Gouma4 ∗ 1Department of Electrical and Computer Engineering, The University of British Columbia, Vancouver, BC V6T1Z4, Canada 2Sensitron Semiconductor, Deer Park, NY 11729, USA 3Department of Electrical and Computer Engineering, SUNY Stony Brook, Stony Brook, NY 11794, USA 4Center for Nanomateri...

Ultrasensitive detection of proteins and sugars at single-cell level

Each cell produces its own responses even if it appears identical to other cells. To analyze these individual cell characteristics, we need to measure trace amounts of molecules in a single cell. Nucleic acids in a single cell can be easily amplified by polymerase chain reaction, but single-cell measurement of proteins and sugars will require de novo techniques. In the present study, we outline...

A compact lab-on-a-chip nanosensor for glycerol detection